Syringomyelia resolution following chiari surgery: A novel scale for communication and research Journal Article
| Authors: | Lara-Reyna, J.; Chae, J.; Tosi, U.; Souweidane, M. M.; Uribe-Cardenas, R.; Greenfield, J. P. |
| Article Title: | Syringomyelia resolution following chiari surgery: A novel scale for communication and research |
| Abstract: | BACKGROUND: The pathophysiological connection between Chiari malformation and syringomyelia is accepted. Debate remains, however, how can we best define changes in syringomyelia following surgery. OBJECTIVE: To introduce a grading system focusing on syrinx reduction based on routinely and reproducible radiological information, and provide a suggestion of the application of this scale for prediction of patient’s prognoses. METHODS: Data from 48 patients with Chiari malformation and syringomyelia were compiled. We calculated syrinx cross-sectional area by approximating an ellipse in the largest axial plane. We compared the percentage of reduction or enlargement following surgery. The percentage change was grouped into four grades: Grade 0 = Increasing size, grade I ≤ 50% reduction, grade II = 50% to 90% reduction, grade III ≥ 90% reduction. RESULTS: A total of 89.6% of patients had syrinx improvement after surgery. A total of 5 patients were grade 0, 14 were grade I, 20 patients were grade II, and 9 patients met criteria for grade III. The mean postoperative syrinx area was 24.1 mm2 (0-169 mm2) with a mean syrinx reduction of 62.7%. CONCLUSION: Radiological improvement of syringomyelia can be mathematically defined and standardized to assist in communication in outcome-based trials. Radiological resolution is expected most patients. Copyright © 2020 by the Congress of Neurological Surgeons. |
| Keywords: | cerebrospinal fluid; posterior fossa; chiari malformation; syringomyelia |
| Journal Title: | Neurosurgery |
| Volume: | 88 |
| Issue: | 1 |
| ISSN: | 0148-396X |
| Publisher: | Wolters Kluwer |
| Date Published: | 2021-01-01 |
| Start Page: | E60 |
| End Page: | E66 |
| Language: | English |
| DOI: | 10.1093/neuros/nyaa326 |
| PUBMED: | 32779709 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 February 2021 -- Source: Scopus |
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