The NCI-MATCH: A national, collaborative precision oncology trial for diverse tumor histologies Journal Article


Authors: Murciano-Goroff, Y. R.; Drilon, A.; Stadler, Z. K.
Article Title: The NCI-MATCH: A national, collaborative precision oncology trial for diverse tumor histologies
Abstract: The NCI-MATCH is a national master protocol trial, published in the Journal of Clinical Oncology, in which diverse tumors are sequenced and patients assigned to treatment. The trial demonstrates the feasibility of identifying rare and common actionable genetic alterations and underscores the strength of academic/community partnerships for improving trial access. © 2020 Elsevier Inc. The NCI-MATCH is a national master protocol trial, published in the Journal of Clinical Oncology, in which diverse tumors are sequenced and patients assigned to treatment. The trial demonstrates the feasibility of identifying rare and common actionable genetic alterations and underscores the strength of academic/community partnerships for improving trial access. © 2020 Elsevier Inc.
Keywords: immunohistochemistry; adult; unclassified drug; gene mutation; clinical protocol; oncology; cancer research; histology; phosphatidylinositol 3 kinase inhibitor; clinical trial (topic); trastuzumab emtansine; dabrafenib; trametinib; high throughput sequencing; afatinib; nivolumab; azd 4547; gsk 2636771; human; priority journal; article; malignant neoplasm; larotrectinib; capivasertib; adavosertib; gsk 263671
Journal Title: Cancer Cell
Volume: 39
Issue: 1
ISSN: 1535-6108
Publisher: Cell Press  
Date Published: 2021-01-11
Start Page: 22
End Page: 24
Language: English
DOI: 10.1016/j.ccell.2020.12.021
PUBMED: 33434511
PROVIDER: scopus
PMCID: PMC10640715
DOI/URL:
Notes: Article -- Export Date: 1 February 2021 -- Source: Scopus
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  1. Zsofia Kinga Stadler
    394 Stadler
  2. Alexander Edward Drilon
    636 Drilon