Trends in chronic opioid therapy among survivors of head and neck cancer Journal Article
| Authors: | Kriplani, A.; Lavery, J. A.; Mishra, A.; Korenstein, D.; Lipitz-Snyderman, A. N.; Boudreau, D. M.; Moryl, N.; Gillespie, E. F.; Salz, T. |
| Article Title: | Trends in chronic opioid therapy among survivors of head and neck cancer |
| Abstract: | Background: Survivors of head and neck cancer (HNC) have increased risk of opioid misuse. Methods: Using Surveillance, Epidemiology and End-Results-Medicare data, we matched adults ≥66 years diagnosed with HNC 2008-2015 with cancer-free controls. We computed odds ratios (OR) for receipt of chronic opioid therapy (COT, claims for ≥90 consecutive days) for HNC survivors compared to controls each year after matching through 2016. Results: The cohort of HNC survivors declined from 5107 in the first year after diagnosis to 604 in the sixth year after diagnosis. For 5 years, rates of COT among HNC survivors exceeded that of controls. Differences between survivors and controls declined each year (ORs: year 1, 4.36; year 2, 2.60; year 3, 2.18; year 4, 1.85; and year 5, 1.35; all P-values <.05). Conclusions: Among older HNC survivors, cancer-associated opioid use in the first years after diagnosis suggests that the benefit of opioids must balance the risk of opioid misuse. © 2020 Wiley Periodicals LLC |
| Keywords: | retrospective studies; head and neck neoplasms; seer program; cancer survivors; opioid epidemic; medicare part d |
| Journal Title: | Head & Neck |
| Volume: | 43 |
| Issue: | 1 |
| ISSN: | 1043-3074 |
| Publisher: | John Wiley & Sons, Inc. |
| Date Published: | 2021-01-01 |
| Start Page: | 223 |
| End Page: | 228 |
| Language: | English |
| DOI: | 10.1002/hed.26478 |
| PUBMED: | 32964530 |
| PROVIDER: | scopus |
| PMCID: | PMC8405132 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 4 January 2021 -- Source: Scopus |
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