Is minimally invasive surgery of lesions in the right superior segments of the liver justified? A multi-institutional study of 245 patients Journal Article


Authors: Gholami, S.; Judge, S. J.; Lee, S. Y.; Mashayekhi, K.; Goh, B. K. P.; Chan, C. Y.; Nuño, M. A.; Gönen, M.; Balachandran, V. P.; Allen, P. J.; Drebin, J. A.; Jarnagin, W. R.; D'Angelica, M. I.; Kingham, T. P.
Article Title: Is minimally invasive surgery of lesions in the right superior segments of the liver justified? A multi-institutional study of 245 patients
Abstract: Background: Controversy exists regarding the safety and feasibility of minimally invasive resection for lesions in segments 7 or 8. We compare outcomes of minimally invasive surgery (MIS) and Open parenchymal sparing liver resections at two high-volume centers. Methods: From 2003 to 2016 we identified patients who underwent MIS or Open resections for lesions in segments 7 or 8 at two institutions (MSKCC and SGH). Outcomes were compared using univariate and multivariate analyses. Results: Two-hundred and forty-five patients underwent resection of lesions in segments 7 or 8 (MIS 30% and Open 70%). Compared to the Open group, the MIS group had longer operative time (223 ± 88 vs 188 ± 72 minutes, P =.003), lower blood loss (297 ± 287 vs 448 ± 670 mL, P =.03), and shorter mean length of stay (5.2 ± 7.4 vs 8.3 ± 11.7 days, P <.001), which remained significant on multivariate analysis. No differences in Pringle time, rate of postoperative complications, or R0 resections were detected. Conclusions: With appropriately selected patients treated by experienced MIS hepatopancreatobiliary surgeons, MIS resection of segments 7 or 8 is safe with similar rates of complications and R0 resections, with significantly less blood loss and shorter length of stay. © 2020 Wiley Periodicals LLC
Keywords: laparoscopic liver resection; liver segments 7/8; minimally invasive surgery liver resection; parenchymal sparing liver resection; posterior-superior liver segments
Journal Title: Journal of Surgical Oncology
Volume: 122
Issue: 7
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2020-12-01
Start Page: 1428
End Page: 1434
Language: English
DOI: 10.1002/jso.26154
PROVIDER: scopus
PMCID: PMC7978501
PUBMED: 33459363
DOI/URL:
Notes: Article -- Export Date: 4 January 2021 -- Source: Scopus
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MSK Authors
  1. Mithat Gonen
    1028 Gonen
  2. Peter Allen
    501 Allen
  3. William R Jarnagin
    903 Jarnagin
  4. T Peter Kingham
    609 Kingham
  5. Jeffrey Adam Drebin
    165 Drebin