Frozen section in thyroid gland follicular neoplasms: It's high time to abandon it! Review
| Authors: | Sanabria, A.; Zafereo, M.; Thompson, L. D. R.; Hernandez-Prera, J. C.; Kowalski, L. P.; Nixon, I. J.; Shaha, A.; Rodrigo, J. P.; Mäkitie, A.; Vander Poorten, V.; Suarez, C.; Zbären, P.; Rinaldo, A.; Ferlito, A. |
| Review Title: | Frozen section in thyroid gland follicular neoplasms: It's high time to abandon it! |
| Abstract: | Thyroid nodules are a very common clinical condition. The 2015 American Thyroid Association (ATA) guidelines recommend surgical excision for Bethesda IV nodules. The use of intraoperative frozen section (FS) has been recommended as a strategy to tailor the extent of the initial surgery. We critically evaluated the literature that discusses the utility and cost-effectiveness of FS to make an intraoperative decision in patients with thyroid nodules classified as follicular neoplasm. FS should not be recommended as a routine intraoperative test to assess for malignancy in thyroid follicular patterned lesions due to its low performance; the high number of deferred results; the inability to adequately assess histologically defining features; the improvements in risk stratification guiding total thyroidectomy; and the low cost-effectiveness of FS. © 2020 Elsevier Ltd |
| Keywords: | carcinoma; thyroidectomy; thyroid nodule; frozen section; follicular neoplasm |
| Journal Title: | Surgical Oncology |
| Volume: | 36 |
| ISSN: | 0960-7404 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2021-03-01 |
| Start Page: | 76 |
| End Page: | 81 |
| Language: | English |
| DOI: | 10.1016/j.suronc.2020.12.005 |
| PROVIDER: | scopus |
| PUBMED: | 33316682 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 4 January 2021 -- Source: Scopus |
