Surveillance endoscopy in the management of hereditary diffuse gastric cancer syndrome Research Letter
| Authors: | Friedman, M.; Adar, T.; Patel, D.; Lauwers, G. Y.; Yoon, S. S.; Mullen, J. T.; Chung, D. C. |
| Title: | Surveillance endoscopy in the management of hereditary diffuse gastric cancer syndrome |
| Abstract: | Hereditary diffuse gastric cancer (HDGC) syndrome results from a germline CDH1 mutation, and microscopic foci of signet-ring carcinoma cells (SRCC) are present in nearly all gastrectomy specimens.1 The lifetime risk of invasive gastric cancer (GC) has been thought to be 70%,2 but recent data have suggested a lower risk of 37%.3 Prophylactic total gastrectomy is considered the standard of care, but many patients choose surveillance endoscopy instead. We sought to define the outcomes in CDH1-positive individuals who pursued endoscopic surveillance. © 2021 AGA Institute |
| Journal Title: | Clinical Gastroenterology and Hepatology |
| Volume: | 19 |
| Issue: | 1 |
| ISSN: | 1542-3565 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2021-01-01 |
| Start Page: | 189 |
| End Page: | 191 |
| Language: | English |
| DOI: | 10.1016/j.cgh.2019.10.033 |
| PUBMED: | 31678201 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Short Survey -- Export Date: 4 January 2021 -- Source: Scopus |
