Management of low grade papillary bladder tumors Journal Article


Authors: Herr, H. W.; Donat, S. M.; Reuter, V. E.
Article Title: Management of low grade papillary bladder tumors
Abstract: Purpose: We evaluated the management and treatment outcomes of low grade papillary bladder tumors. Materials and Methods: We evaluated 215 patients diagnosed with low grade and noninvasive papillary bladder tumors, and followed them every 6 months with flexible cystoscopy for 6 to 10 or more years. Tumor recurrence was treated with transurethral resection or outpatient cystoscopic fulguration. Results: Of the 215 patients 143 (67%) had at least 1 recurrence (positive cystoscopy). With a median followup of 8 years tumor recurrences averaged 6.2 (range 1 to 19) requiring 0.34 transurethral resections per year or 1 transurethral resection every 3 years, or 0.61 fulgurations or 1 fulguration approximately every 2 years. There were 17 patients (8%) who had progression in grade or stage and 1 patient (0.5%) died of bladder cancer. Patients most likely to have recurrence had multiple tumors, low grade (TaLG) carcinoma or tumor at first followup cystoscopy. Conclusions: Surveillance cystoscopy at 6-month intervals coupled with outpatient fulguration controls recurrent tumors and reduces the therapeutic burden for patients diagnosed with low grade papillary bladder tumors. © 2007 American Urological Association.
Keywords: adult; treatment outcome; aged; middle aged; survival analysis; major clinical study; cancer staging; follow up; follow-up studies; neoplasm staging; cancer grading; neoplasm recurrence, local; carcinoma, papillary; urinary bladder neoplasms; tumor recurrence; urinary bladder; reoperation; neoplasm invasiveness; cystoscopy; papilloma; transurethral resection; carcinoma, transitional cell; electrocoagulation; bladder papilloma
Journal Title: Journal of Urology
Volume: 178
Issue: 4
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 2007-10-01
Start Page: 1201
End Page: 1205
Language: English
DOI: 10.1016/j.juro.2007.05.148
PUBMED: 17698090
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 18" - "Export Date: 17 November 2011" - "CODEN: JOURA" - "Source: Scopus"
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  1. Sherri M Donat
    174 Donat
  2. Victor Reuter
    1228 Reuter
  3. Harry W Herr
    594 Herr