Urachal carcinoma: Contemporary surgical outcomes Journal Article
| Authors: | Herr, H. W.; Bochner, B. H.; Sharp, D.; Dalbagni, G.; Reuter, V. E. |
| Article Title: | Urachal carcinoma: Contemporary surgical outcomes |
| Abstract: | Purpose: We determined surgical outcomes in a contemporary series of patients who underwent surgery for urachal carcinoma. Materials and Methods: A cohort of 50 patients with clinically staged localized urachal carcinoma underwent extended partial cystectomy, including the urachal tumor mass and entire urachus. The patients were followed a median of 5+ years for cancer-free survival. Results: Of the 50 patients 93% (26 of 28) with tumor confined to the urachus and bladder survived compared to 69% (9 of 13) with extravesical or peri-urachal tumor invasion and none (9 patients) with tumor invasion into the peritoneal cavity. Local recurrence was noted in 9 patients (18%) and 2 had salvage therapy. The most significant predictors of survival were pathological tumor stage and negative surgical margins. Conclusions: Wide resection of the tumor mass and entire urachus resulting in negative soft tissue and bladder margins cures the majority of nonmetastatic urachal cancers. © 2007 American Urological Association. |
| Keywords: | adolescent; adult; cancer survival; aged; aged, 80 and over; disease-free survival; middle aged; cancer surgery; major clinical study; cancer recurrence; salvage therapy; cancer patient; cancer staging; outcome assessment; follow up; neoplasm staging; metastasis; bladder cancer; bladder tumor; urinary bladder neoplasms; cancer invasion; soft tissue; cystectomy; carcinoma; multivariate analysis; neoplasm invasiveness; urachal carcinoma; urachus; peritoneal cavity |
| Journal Title: | Journal of Urology |
| Volume: | 178 |
| Issue: | 1 |
| ISSN: | 0022-5347 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2007-07-01 |
| Start Page: | 74 |
| End Page: | 78 |
| Language: | English |
| DOI: | 10.1016/j.juro.2007.03.022 |
| PUBMED: | 17499279 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 17" - "Export Date: 17 November 2011" - "CODEN: JOURA" - "Source: Scopus" |
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