Yttrium 90 microsphere selective internal radiation treatment of hepatic colorectal metastases Journal Article
| Authors: | Gulec, S. A.; Fong, Y. |
| Article Title: | Yttrium 90 microsphere selective internal radiation treatment of hepatic colorectal metastases |
| Abstract: | Objective: To discuss the basic concepts involved in the development of yttrium 90 (Y-90) microsphere selective internal radiation treatment and review the clinical data pertaining to its application in hepatic colorectal cancer metastases. Data Sources: Published studies and scientific paper presentations. Study Selection: Randomized clinical studies and retrospective reviews. Conclusions: Selective internal radiation treatment is a promising new modality in the treatment of patients with hepatic colorectal cancer metastases as part of a multimodality approach. A chemo-selective internal radiation treatment neoadjuvant approach has a potential to improve therapeutic outcomes. Clinical studies in neoadjuvant and salvage settings are needed for more concrete outcome data and design of optimal multimodality treatment strategies. ©2007 American Medical Association. All rights reserved. |
| Keywords: | treatment outcome; retrospective studies; unclassified drug; neutropenia; review; salvage therapy; bevacizumab; fluorouracil; multimodality cancer therapy; nonhuman; liver neoplasms; cancer patient; cancer radiotherapy; neoadjuvant therapy; radiopharmaceuticals; colorectal cancer; metastasis; liver toxicity; nausea; colonic neoplasms; retrospective study; cetuximab; irinotecan; abdominal pain; drug dose escalation; fever; narcotic analgesic agent; clinical study; randomized controlled trials; folinic acid; stomach ulcer; brachytherapy; liver cancer; oxaliplatin; lethargy; floxuridine; rectal neoplasms; yttrium radioisotopes; duodenum ulcer; microsphere; yttrium 90; microspheres; yttrium 90 microsphere; hepatic colorectal cancer |
| Journal Title: | Archives of Surgery |
| Volume: | 142 |
| Issue: | 7 |
| ISSN: | 0004-0010 |
| Publisher: | American Medical Association |
| Date Published: | 2007-07-01 |
| Start Page: | 675 |
| End Page: | 682 |
| Language: | English |
| DOI: | 10.1001/archsurg.142.7.675 |
| PUBMED: | 17638807 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 27" - "Export Date: 17 November 2011" - "CODEN: ARSUA" - "Source: Scopus" |
