Infectious disease complications in patients with cancer Review
| Authors: | Seo, S. K.; Liu, C.; Dadwal, S. S. |
| Review Title: | Infectious disease complications in patients with cancer |
| Abstract: | Critically ill patients with cancer are vulnerable to infections because of the underlying malignancy, tumor-directed therapy, immunosuppression, breaches in mucosa or skin, malnutrition, and other factors. Neutropenia remains the most important risk factor for infection. Infectious complications occurring in critically ill patients with cancer can affect the bloodstream, lungs, gastrointestinal tract, central nervous system, urinary tract, and the skin. Pneumonias are the leading cause of infection in patients with cancer admitted to the intensive care unit. Consideration of opportunistic pathogens in the differential diagnosis is important in patients with impaired cellular and/or humoral immunity or compromised splenic function. © 2020 Elsevier Inc. |
| Keywords: | fludarabine; neutropenia; review; cytotoxic agent; nonhuman; cancer patient; rituximab; temozolomide; drug megadose; infection; nephrotoxicity; bone marrow suppression; differential diagnosis; aciclovir; alkylating agent; herpes simplex; herpes zoster; pneumocystis pneumonia; fever; pneumonia; intensive care; folinic acid; urinary tract infection; sepsis; colitis; cidofovir; clostridium difficile infection; vancomycin; corticosteroid; cotrimoxazole; metronidazole; catheter infection; meningitis; fluconazole; foscarnet; ganciclovir; adenovirus infection; candidiasis; cytomegalovirus infection; mycosis; critical care; voriconazole; echinocandin; aspergillosis; lung aspergillosis; respiratory tract infection; alemtuzumab; mycobacteriosis; tuberculosis; skin infection; catheter removal; infectious complication; valganciclovir; histoplasmosis; central nervous system infection; cefepime; bacterial pneumonia; blood culture; tumor necrosis factor inhibitor; herpes virus infection; ceftazidime; infectious diarrhea; soft tissue infection; carbapenem; infliximab; community acquired pneumonia; brain abscess; atypical mycobacteriosis; neutropenic enterocolitis; pneumocystosis; amphotericin b; immunocompromised; ibrutinib; antimicrobial stewardship; cancer; human; priority journal; fidaxomicin; nocardiosis; pyrimethamine; mucormycosis; solid malignant neoplasm; bruton tyrosine kinase inhibitor; sulfadiazine; coronavirus disease 2019; cerebral toxoplasmosis; cytomegalovirus colitis; fusariosis; strongyloides hyperinfection syndrome |
| Journal Title: | Critical Care Clinics |
| Volume: | 37 |
| Issue: | 1 |
| ISSN: | 0749-0704 |
| Publisher: | W.B. Saunders Co. |
| Date Published: | 2021-01-01 |
| Start Page: | 69 |
| End Page: | 84 |
| Language: | English |
| DOI: | 10.1016/j.ccc.2020.09.001 |
| PUBMED: | 33190776 |
| PROVIDER: | scopus |
| PMCID: | PMC8294629 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 December 2020 -- Source: Scopus |
