Should WEE(1) CHK(1) in on the FAM(122A)ily? Editorial


Authors: Caeser, R.; Sen, T.
Title: Should WEE(1) CHK(1) in on the FAM(122A)ily?
Abstract: Li et al. (2020) elucidate the resistance mechanisms to small-molecule inhibitors targeting the G2/M cell cycle checkpoint kinase, CHK1, in a variety of non-small cell lung cancer cell lines using CRISPR-mediated genetic approaches and identify biomarkers of response. © 2020 Elsevier Inc. Li et al. (2020) elucidate the resistance mechanisms to small-molecule inhibitors targeting G2-M cell cycle checkpoint kinase, CHK1, in a variety of non-small cell lung cancer (NSCLC) cell lines using CRISPR-mediated genetic approaches and identify biomarkers of response. © 2020 Elsevier Inc.
Keywords: genetics; cell cycle protein; metabolism; cell cycle proteins; protein kinases; carcinoma, non-small-cell lung; lung neoplasms; cell line, tumor; phosphorylation; lung tumor; tumor cell line; checkpoint kinase 1; protein kinase; non small cell lung cancer; humans; human
Journal Title: Molecular Cell
Volume: 80
Issue: 3
ISSN: 1097-2765
Publisher: Cell Press  
Date Published: 2020-11-05
Start Page: 377
End Page: 378
Language: English
DOI: 10.1016/j.molcel.2020.10.011
PUBMED: 33157011
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 December 2020 -- Source: Scopus
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  1. Triparna Sen
    56 Sen
  2. Rebecca Caeser
    14 Caeser