PD-L1 blockade therapy: Location, location, location Editorial


Authors: Brown, C. C.; Wolchok, J. D.
Title: PD-L1 blockade therapy: Location, location, location
Abstract: The mechanisms by which PD-1/PD-L1 inhibition elicits anti-tumor immunity are not fully understood. In this issue of Cancer Cell, Dammeijer et al. address the role of PD-L1 inhibition specifically within the tumor-draining lymph node, identifying a potential role for PD-L1 expressing dendritic cells within the lymph node in regulation of anti-tumor immune responses. © 2020 Elsevier Inc. The mechanisms by which PD-1/PD-L1 inhibition elicits anti-tumor immunity are not fully understood. In this issue of Cancer Cell, Dammeijer et al. address the role of PD-L1 inhibition specifically within the tumor-draining lymph node, identifying a potential role for PD-L1 expressing dendritic cells within the lymph node in regulation of anti-tumor immune responses. © 2020 Elsevier Inc.
Journal Title: Cancer Cell
Volume: 38
Issue: 5
ISSN: 1535-6108
Publisher: Cell Press  
Date Published: 2020-11-09
Start Page: 615
End Page: 617
Language: English
DOI: 10.1016/j.ccell.2020.10.017
PUBMED: 33171125
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 December 2020 -- Source: Scopus
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  1. Jedd D Wolchok
    905 Wolchok
  2. Chrysothemis Celia Margaret Brown
    17 Brown