Nested variant of urothelial carcinoma Journal Article
| Authors: | Dhall, D.; Al-Ahmadie, H.; Olgac, S. |
| Article Title: | Nested variant of urothelial carcinoma |
| Abstract: | Nested variant of urothelial carcinoma is a rare neoplasm that is histologically characterized by large numbers of small, closely packed, haphazardly arranged, poorly defined, confluent irregular nests of bland-appearing urothelial cells infiltrating the lamina propria and the muscularis propria. Due to the cells' deceptively bland appearance, the tumors are sometimes misdiagnosed as benign lesions, leading in some cases to a significant delay in establishing the correct diagnosis and thus contributing to this neoplasm's advanced stage. Nested variant of urothelial carcinoma must be differentiated from the benign proliferative lesions of urothelium, such as von Brunn nests, cystitis cystica, cystitis glandularis, nephrogenic adenoma, inverted papilloma, and paraganglioma. |
| Keywords: | immunohistochemistry; adult; controlled study; human tissue; aged; aged, 80 and over; middle aged; human cell; histopathology; advanced cancer; follow up; diagnostic accuracy; paraganglioma; cell infiltration; diagnosis, differential; differential diagnosis; genetic variability; urinary bladder neoplasms; urothelium; urothelial carcinoma; diagnostic error; epithelial cells; short survey; keratin-20; carcinoma, transitional cell; cystitis; keratin-7; urinary tract carcinoma; cytodiagnosis; cytoarchitecture; lamina propria; cystitis cystica; glandular cystitis; inverted papilloma; muscularis propria; von brunn nest |
| Journal Title: | Archives of Pathology & Laboratory Medicine |
| Volume: | 131 |
| Issue: | 11 |
| ISSN: | 0003-9985 |
| Publisher: | College of American Pathologists |
| Date Published: | 2007-11-01 |
| Start Page: | 1725 |
| End Page: | 1727 |
| Language: | English |
| PUBMED: | 17979494 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 17 November 2011" - "CODEN: ARPAA" - "Source: Scopus" |
