Tl-201 stress tests and homeland security Journal Article


Authors: Dauer, L. T.; Williamson, M. J.; St. Germain, J.; Strauss, H. W.
Article Title: Tl-201 stress tests and homeland security
Abstract: Background: This study estimates the length of time a patient might trigger security radiation detection devices after thallium 201 cardiac imaging. The US Department of Homeland Security is supporting the purchase and deployment of radiation detection pagers and portal monitors. Concurrently, there are an increasing number of cardiac perfusion imaging studies being performed using Tl-201. Therefore there is a higher probability that patients who have undergone nuclear medicine procedures could trigger alarms resulting in security questions. Methods and Results: The length of time patients could trigger such devices is estimated based on the radiopharmacokinetics of Tl-201 and potential radioactive contaminants as well as the capabilities of current sensitive radiation detection devices, assuming the radioactive sources are distributed in and attenuated by the patient. It is estimated that patients may trigger portable pager devices for up to 33 days and may trigger portal detectors for up to 51 days after studies using Tl-201. This is much longer than length of time for a patient to trigger such alarms after technetium 99m myocardial imaging tests, which is potentially up to 6 days. Conclusions: It should be standard practice for patients to be issued information cards that indicate the potential time for triggering security radiation detectors after diagnostic cardiac procedures involving the use of Tl-201 or other radiopharmaceuticals. © 2007 American Society of Nuclear Cardiology.
Keywords: united states; technetium 99m; radiopharmaceuticals; radiation; calibration; time factors; patient information; kinetics; probability; radioactivity; scintiscanning; methoxy isobutyl isonitrile technetium tc 99m; radiometry; phantoms, imaging; half life time; heart; ischemic heart disease; thallium 201; myocardium; government regulation; tetrofosmin tc 99m; thallium radioisotopes; perfusion; travel; thallium; radiation detection; bioequivalence; radiation attenuation; perfusion imaging; security; stress tests; lead 203; molybdenum 99; thallium chloride tl 201; heart perfusion; law enforcement; nuclear safety; pharmacologic stress testing; radioactive contamination; security measures; united states government agencies
Journal Title: Journal of Nuclear Cardiology
Volume: 14
Issue: 4
ISSN: 1071-3581
Publisher: Springer  
Date Published: 2007-07-01
Start Page: 582
End Page: 588
Language: English
DOI: 10.1016/j.nuclcard.2007.04.021
PUBMED: 17679068
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 5" - "Export Date: 17 November 2011" - "CODEN: JNCAE" - "Source: Scopus"
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  1. Harry W Strauss
    147 Strauss
  2. Lawrence Dauer
    117 Dauer