Changing the default: A prospective study of reducing discharge opioid prescription after lumpectomy and sentinel node biopsy Journal Article


Authors: Moo, T. A.; Pawloski, K. R.; Sevilimedu, V.; Charyn, J.; Simon, B. A.; Sclafani, L. M.; Plitas, G.; Barrio, A. V.; Kirstein, L. J.; Van Zee, K. J.; Morrow, M.
Article Title: Changing the default: A prospective study of reducing discharge opioid prescription after lumpectomy and sentinel node biopsy
Abstract: Background: Whether routinely prescribed opioids are necessary for pain control after discharge among lumpectomy/sentinel node biopsy (Lump/SLNB) patients is unclear. We hypothesize that Lump/SLNB patients could be discharged without opioids, with a failure rate < 10%. This study prospectively examines outcomes after changing standard discharge prescription from an opioid/non-steroidal anti-inflammatory drug (NSAID) to NSAID/acetaminophen. Patients and Methods: Standard discharge pain medication orders included opioids in the first 3-month study period and were changed to NSAID/acetaminophen in the second 3-month period. Patient-reported medication consumption and pain scores were collected by post-discharge survey. Frequency of discharge with opioid, NSAID/acetaminophen failure rate, opioid use, and pain scores were examined. Results: From May to October 2019, 663 patients had Lump/SLNB: 371 in the opioid study period and 292 in the NSAID period. In the opioid period, 92% (342/371) of patients were prescribed an opioid at discharge; of 142 patients who documented opioid use on the survey, 86 (61%) used zero tablets. Among 56 (39%) patients who used opioids, the median number taken by POD 5 was 4. After the change to NSAID/acetaminophen, rates of opioid prescription decreased to 14% (41/292). The NSAID/acetaminophen failure rate was 2% (5/251). Among survey respondents, there was no significant difference in the maximum reported pain scores (POD 1–5) between the opioid period and the NSAID period (p = 0.7). Conclusions: In Lump/SLNB patients, a change to default discharge with NSAID/acetaminophen resulted in a 78% absolute reduction in opioid prescription, with a failure rate of 2% and no difference in patient-reported pain scores. Most Lump/SLNB patients can be discharged with NSAID/acetaminophen. © 2020, Society of Surgical Oncology.
Journal Title: Annals of Surgical Oncology
Volume: 27
Issue: 12
ISSN: 1068-9265
Publisher: Springer  
Date Published: 2020-11-01
Start Page: 4637
End Page: 4642
Language: English
DOI: 10.1245/s10434-020-08886-9
PUBMED: 32734370
PROVIDER: scopus
PMCID: PMC7554186
DOI/URL:
Notes: Article -- Export Date: 2 November 2020 -- Source: Scopus
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MSK Authors
  1. Andrea Veronica Barrio
    134 Barrio
  2. Monica Morrow
    772 Morrow
  3. Kimberly J Van Zee
    293 Van Zee
  4. George Plitas
    107 Plitas
  5. Tracy-Ann Moo
    96 Moo
  6. Brett Andrew Simon
    50 Simon
  7. Jillian Rebecca Charyn
    8 Charyn