Unified cross-modality feature disentangler for unsupervised multi-domain MRI abdomen organs segmentation Conference Paper


Authors: Jiang, J.; Veeraraghavan, H.
Title: Unified cross-modality feature disentangler for unsupervised multi-domain MRI abdomen organs segmentation
Conference Title: 23rd International Conference of Medical Image Computing and Computer Assisted Intervention (MICCAI 2020)
Abstract: Our contribution is a unified cross-modality feature disentagling approach for multi-domain image translation and multiple organ segmentation. Using CT as the labeled source domain, our approach learns to segment multi-modal (T1-weighted and T2-weighted) MRI having no labeled data. Our approach uses a variational auto-encoder (VAE) to disentangle the image content from style. The VAE constrains the style feature encoding to match a universal prior (Gaussian) that is assumed to span the styles of all the source and target modalities. The extracted image style is converted into a latent style scaling code, which modulates the generator to produce multi-modality images according to the target domain code from the image content features. Finally, we introduce a joint distribution matching discriminator that combines the translated images with task-relevant segmentation probability maps to further constrain and regularize image-to-image (I2I) translations. We performed extensive comparisons to multiple state-of-the-art I2I translation and segmentation methods. Our approach resulted in the lowest average multi-domain image reconstruction error of 1.34 ± 0.04. Our approach produced an average Dice similarity coefficient (DSC) of 0.85 for T1w and 0.90 for T2w MRI for multi-organ segmentation, which was highly comparable to a fully supervised MRI multi-organ segmentation network (DSC of 0.86 for T1w and 0.90 for T2w MRI). © 2020, Springer Nature Switzerland AG.
Keywords: computerized tomography; medical imaging; medical computing; image reconstruction; image segmentation; segmentation methods; probability distributions; abdominal organs; codes (symbols); signal encoding; similarity coefficients; disentagled networks; multi-domain translation; unsupervised multi-modal mri segmentation; image translation; joint distributions; multi modality image; multi-organ segmentations; organ segmentation; probability maps
Journal Title Lecture Notes in Computer Science
Volume: 12262
Conference Dates: 2020 Oct 4-8
Conference Location: Lima, Peru
ISBN: 0302-9743
Publisher: Springer  
Date Published: 2020-01-01
Start Page: 347
End Page: 358
Language: English
DOI: 10.1007/978-3-030-59713-9_34
PROVIDER: scopus
PUBMED: 33364627
PMCID: PMC7757792
DOI/URL:
Notes: Conference Paper -- Export Date: 2 November 2020 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Jue Jiang
    78 Jiang