Highly sensitive determination of chloride ions in serum using a Rayleigh light scattering technique Journal Article


Authors: Chen, J. W.; Yang, C. S.; Ren, F. L.; Xiao, J. B.; Xu, M.
Article Title: Highly sensitive determination of chloride ions in serum using a Rayleigh light scattering technique
Abstract: A Rayleigh light scattering technique to determine chloride ions in serum was developed. Chloride ions were found to bind Ag+ forming an AgCl aggregate that produced intense Rayleigh scattering light. The effects of factors such as acidity, ionic strength and coexisting interferents on the RLS of the AgCl aggregate were investigated. The solution pH almost did not affect the production of RLS, and few foreign biologically relevant species interfered with the detection of chloride ions. The Rayleigh scattering light intensity at the maximum peak of 571 nm was linear to the concentration of chloride ions in the range of 35.5-71.0 ng mL-1 with a detection limit of 14.2 ng mL-1. The method was applied to determine chloride ions in serum, showing high sensitivity and accuracy compared with the clinically used ion-selective electrode method. © 2007 IOP Publishing Ltd.
Keywords: serum; electrodes; drug products; light scattering; determination; ph effects; chloride ion; rayleigh light scattering; concentration (process); ions
Journal Title: Measurement Science and Technology
Volume: 18
Issue: 7
ISSN: 0957-0233
Publisher: IOP Publishing Ltd  
Date Published: 2007-07-01
Start Page: 2043
End Page: 2047
Language: English
DOI: 10.1088/0957-0233/18/7/034
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 6" - "Export Date: 17 November 2011" - "Art. No.: 034" - "CODEN: MSTCE" - "Source: Scopus"
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  1. Ming Xu
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