Thymic malignancy—Updates in staging and management Review
| Authors: | Rappaport, J. M. P.; Huang, J.; Ahmad, U. |
| Review Title: | Thymic malignancy—Updates in staging and management |
| Abstract: | Thymomas are relatively indolent tumors that present with locally advanced disease in 30% of the patients. Thymic carcinoma is a more aggressive histology with shorter disease-free and overall survival. Early-stage tumors are managed best with complete resection. Multimodal therapy is the standard of care for locally advanced tumors and neoadjuvant therapy may help improve respectability. Stage and complete resection are the strongest prognostic factors for long-term survival. Based on early experience, targeted and immunotherapies have shown limited promise in advanced disease. © 2020 Elsevier Inc. |
| Keywords: | chemotherapy; thymoma; chemoradiation; thymic carcinoma; neoadjuvant; multimodal therapy |
| Journal Title: | Surgical Oncology Clinics of North America |
| Volume: | 29 |
| Issue: | 4 |
| ISSN: | 1055-3207 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2020-10-01 |
| Start Page: | 581 |
| End Page: | 601 |
| Language: | English |
| DOI: | 10.1016/j.soc.2020.06.010 |
| PUBMED: | 32883460 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 October 2020 -- Source: Scopus |
