Adult and pediatric testicular teratoma Journal Article

  


Authors: Carver, B. S.; Al-Ahmadie, H.; Sheinfeld, J.
Article Title: Adult and pediatric testicular teratoma
Abstract: Although pure testicular teratomas in prepubertal boys have not been reported to metastasize, testicular teratomas in adults are associated with clinical metastases in 60% of cases. Teratoma has a diverse biological potential, with propensity for local growth, distant metastases, and transformation to somatic malignant cell types. Teratoma is frequently found associated with other nonseminomatous histologies and is present in the retroperitoneum in 40% of postchemotherapy retroperitoneal lymph node dissections. Because of the chemoresitant nature of teratomas, complete surgical resection is the treatment of choice. Since the biology of teratoma is unpredictable and it is frequently found in the retroperitoneum following chemotherapy for nonseminomatous germ-cell tumors, complete control of the retroperitoneum is advocated for all patients regardless of residual mass size. © 2007 Elsevier Inc. All rights reserved.
Keywords: immunohistochemistry; adult; cancer survival; treatment outcome; cancer surgery; genetics; pathogenesis; review; advanced cancer; cancer staging; cancer incidence; lymph node dissection; neoplasm staging; metastasis; tumor marker; echography; testicular neoplasms; teratoma; orchiectomy; comparative genomic hybridization; karyotyping; clinical trials; non seminomatous germinoma; alpha fetoprotein; testis teratoma
Journal Title: Urologic Clinics of North America
Volume: 34
Issue: 2
ISSN: 0094-0143
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 2007-05-01
Start Page: 245
End Page: 251
Language: English
DOI: 10.1016/j.ucl.2007.02.013
PUBMED: 17484929
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-34247579077&partnerID=40&md5=e9c0d7c943edf83b2ae75035b86f2960
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "CODEN: UCNAD" - "Source: Scopus"
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MSK Authors
  1. Joel Sheinfeld
    254 Sheinfeld
  2. Brett Stewart Carver
    143 Carver
  3. Hikmat Al-Ahmadie
    660 Al-Ahmadie
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