C-glycosylation of substituted heterocycles under Friedel-Crafts conditions (I): A two-step synthesis of the thieno[3,4-d]pyrimidine c-nucleoside analog of inosine Journal Article
| Authors: | Rao, S. P.; Rao, K. V. B.; Otter, B. A.; Klein, R. S.; Ren, W. Y. |
| Article Title: | C-glycosylation of substituted heterocycles under Friedel-Crafts conditions (I): A two-step synthesis of the thieno[3,4-d]pyrimidine c-nucleoside analog of inosine |
| Abstract: | Direct stannic chloride catalyzed C-glycosylation of N-formyl-4-amino-3-carboalkoxy thiophenes with 1-O-acetyl-tri-O-benzoyl-β-D-ribofuranose, followed by annelation of a fused pyrimidone ring upon treatment with ammonia, constitutes a short approach to the synthesis of a new C-nucleoside inosine analog. © 1988. |
| Keywords: | unclassified drug; nonhuman; drug synthesis; nuclear magnetic resonance; 6 oxothieno[3,4 d]pyrimidine riboside |
| Journal Title: | Tetrahedron Letters |
| Volume: | 29 |
| Issue: | 29 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 1988-01-01 |
| Start Page: | 3537 |
| End Page: | 3540 |
| Language: | English |
| DOI: | 10.1016/0040-4039(88)85286-9 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 6 August 2020 -- Source: Scopus |
