A novel stereospecific radical cyclization of 2′,3′-O-isopropylideneuridine and -adenosine 5′-aldehyde to the corresponding 6,5′-cyclodihydrouridine and 8,5′-cycloadenosine derivatives Journal Article
| Authors: | Sugawara, T.; Otter, B. A.; Ueda, T. |
| Article Title: | A novel stereospecific radical cyclization of 2′,3′-O-isopropylideneuridine and -adenosine 5′-aldehyde to the corresponding 6,5′-cyclodihydrouridine and 8,5′-cycloadenosine derivatives |
| Abstract: | Treatment of 2′,3′-O-isopropylideneuridine 5′-aldehyde with tributyltin hydride in the presence of azobisisobutyronitrile affords (6S,5′S)-6,5′-cyclo-5,6-dihydro-2′,3′-O-isopropylideneuridine in a stereospecific manner. A similar reaction with N6-benzoyl-2′,3′-O-isopropylideneadenosine 5′-aldehyde leads to the corresponding 8,5′-cycloadenosine. © 1988. |
| Journal Title: | Tetrahedron Letters |
| Volume: | 29 |
| Issue: | 1 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 1988-01-01 |
| Start Page: | 75 |
| End Page: | 78 |
| Language: | English |
| DOI: | 10.1016/0040-4039(88)80020-0 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 6 August 2020 -- Source: Scopus |
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