Infection with human T-cell leukemia virus type I in patients with leukemia Journal Article


Authors: Minamoto, G. Y.; Gold, J. W. M.; Scheinberg, D. A.; Hardy, W. D.; Chein, N.; Zuckerman, E.; Reich, L.; Dietz, K.; Gee, T.; Hoffer, J.; Mayer, K.; Gabrilove, J.; Clarkson, B.; Armstrong, D.
Article Title: Infection with human T-cell leukemia virus type I in patients with leukemia
Abstract: Among 211 adults with leukemia who received multiple transfusions, 6 were found to be seropositive for human T-cell leukemia virus Type I (HTLV-I). Before the positive serum specimens were obtained, these patients received a mean of 14 units of red cells and 78 units of platelets. Seroconversion could be documented in three patients. None of the 6 patients seropositive for HTLV-I had a T-cell leukemia, other illnesses attributable to HTLV-I infection, or risk factors for HTLV-I infection other than transfusion: none were seropositive for human immunodeficiency virus. Patients with leukemia who receive multiple transfusions appear to be at risk for HTLV-I infection. (N Engl J Med 1988; 318: 219–22.) © 1988, Massachusetts Medical Society. All rights reserved.
Keywords: leukemia; major clinical study; blood; blood transfusion; t cell leukemia; human
Journal Title: New England Journal of Medicine
Volume: 318
Issue: 4
ISSN: 0028-4793
Publisher: Massachusetts Medical Society  
Date Published: 1988-01-28
Start Page: 219
End Page: 222
Language: English
DOI: 10.1056/nejm198801283180405
PUBMED: 2892132
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
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MSK Authors
  1. Lilian M Reich
    99 Reich
  2. Bayard Clarkson
    220 Clarkson
  3. Donald Armstrong
    242 Armstrong
  4. Janice Gabrilove
    122 Gabrilove
  5. Nancy S Chein
    12 Chein
  6. Klaus   Mayer
    18 Mayer
  7. Timothy Gee
    46 Gee
  8. Jonathan W. M. Gold
    73 Gold
  9. William D Hardy
    25 Hardy