Neurologic complications of immunosuppressive agents Journal Article


Authors: Walker, R. W.; Brochstein, J. A.
Article Title: Neurologic complications of immunosuppressive agents
Abstract: The immunosuppressive agents that are an integral part of organ transplantation serve to protect grafts from rejection as well as to prevent or treat GVHD. They include CsA, corticosteroids, OKT3 monoclonal antibody, HDARA-C, azathioprine, and ATG. Of these, all but azathioprine and ATG have direct neurologic complications that are due to the drugs themselves and not just excessive immune suppression. With increasing success in solid organ and bone marrow transplantation and increasing patient survival, one can expect to see more patients who suffer neurologic toxicity.
Keywords: prednisone; review; cytarabine; methotrexate; neurotoxicity; neuropathy; dexamethasone; azathioprine; seizure; ataxia; cyclosporin; leukoencephalopathy; immunosuppressive agent; okt 3; human; meprednisone
Journal Title: Neurologic Clinics
Volume: 6
Issue: 2
ISSN: 0733-8619
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 1988-05-01
Start Page: 261
End Page: 278
Language: English
DOI: 10.1016/s0733-8619(18)30869-7
PUBMED: 3138519
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 6 August 2020 -- Source: Scopus
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  1. Russell W. Walker
    38 Walker