Primitive neuroectodermal tumors of the chest wall Journal Article


Authors: Stefanko, J.; Turnbull, A. D.; Helson, L.; Lieberman, P.; Martini, N.
Article Title: Primitive neuroectodermal tumors of the chest wall
Abstract: Primitive neuroectodermal tumor (PNET) is a rare, highly malignant small‐cell neoplasm that most often arises from the chest wall or paravertebral region. A patient is described from whom resection, intensive chemotherapy, and bone marrow transplant were unsuccessful. Eleven patients were treated between 1975 and 1985; there was only one long term survivor (48 months) despite intensive multidisciplinary treatment. The median survival of 49 published cases was 9 months. Conservative resection minimizing disability, radiotherapy, and intensive chemotherapy remain valid options, but use of experimental agents as part of intial therapy seems justified. The role of autologous marrow transplant remains unclear. Copyright © 1988 Wiley‐Liss, Inc., A Wiley Company
Keywords: adult; cancer chemotherapy; case report; radiotherapy; histology; bone marrow transplantation; thorax wall tumor; neuroectoderm tumor; ultrastructure; neuroectodermal tumor; human; female; priority journal; small cell tumor; chest wall tumor
Journal Title: Journal of Surgical Oncology
Volume: 37
Issue: 1
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 1988-01-01
Start Page: 33
End Page: 37
Language: English
DOI: 10.1002/jso.2930370110
PUBMED: 2826923
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
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  1. Nael   Martini
    105 Martini
  2. Lawrence Helson
    26 Helson