Cisplatin in the treatment of recurrent childhood primary brain tumors Journal Article


Authors: Walker, R. W.; Allen, J. C.
Article Title: Cisplatin in the treatment of recurrent childhood primary brain tumors
Abstract: Thirty-three patients were treated with intravenous (IV) cisplatin (CPDD) of whom 32 were considered evaluable. There were 14 medulloblastomas, five primitive neuroectodermal tumors (PNET), nine gliomas, three ependymomas, and one germ cell tumor. The overall response rate was 13 of 32 (41%). Eleven responses (five complete [CR], five partial [PR], one mixed [MR]) were noted in the patients with medulloblastoma. The response rate within this group was 79%. Toxicity was tolerable, although it precluded further therapy in five patients.
Keywords: child; clinical article; cisplatin; glioma; childhood cancer; tumor recurrence; medulloblastoma; ependymoma; brain cancer; neuroectoderm tumor; intravenous drug administration; human
Journal Title: Journal of Clinical Oncology
Volume: 6
Issue: 1
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 1988-01-01
Start Page: 62
End Page: 66
Language: English
DOI: 10.1200/jco.1988.6.1.62
PUBMED: 2826716
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Russell W. Walker
    38 Walker