Iridium-192 implants for primary breast cancer: Experience with placement at the time of wide local excision Journal Article


Authors: McCormick, B.; Wesson, M. F.; Cox, L.; Osborne, M. P.; Petrek, J. A.; Kinne, D. W.
Article Title: Iridium-192 implants for primary breast cancer: Experience with placement at the time of wide local excision
Abstract: An Ir-192 boost is a technique frequently used to deliver an additional dose of radiation therapy to the tumor bed following breast conserving surgery and combined with external beam radiation therapy to the entire breast for patients with early breast cancer. Traditionally these catheters are placed following completion of 4500-5000 cGy, as a separate procedure. This paper described a Pilot Study identifying placement of the catheters at the time of primary wide local excision, or re-excision in 52 patients. The key to the success of this technique is the achievement of complete hemostasis in the primary cavity, the presence of the radiation oncologist during the surgical procedure itself, and closure of the wound prior to placement of the catheters. Details of the technique, and preliminary patient results are presented. © 1988.
Keywords: adult; aged; major clinical study; combined modality therapy; methodology; intraoperative care; lymph node excision; mastectomy; breast neoplasms; pilot projects; breast carcinoma; reoperation; brachytherapy; radioisotope; iridium 192; radioisotope therapy; iridium radioisotopes; middle age; human; female; priority journal; conservation of breast; perioperative breast implant
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Volume: 15
Issue: 3
ISSN: 0360-3016
Publisher: Elsevier Inc.  
Date Published: 1988-09-01
Start Page: 745
End Page: 748
Language: English
DOI: 10.1016/0360-3016(88)90320-3
PUBMED: 3417493
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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MSK Authors
  1. Jeanne Ann Petrek
    91 Petrek
  2. Beryl McCormick
    371 McCormick
  3. David Kinne
    64 Kinne
  4. Louise Cox
    8 Cox
  5. Michael P. Osborne
    61 Osborne