Massive solitary tophus containing calcium pyrophosphate dihydrate crystals at the acromioclavicular joint Journal Article


Authors: Marcove, R. C.; Wolfe, S. W.; Healey, J. H.; Huvos, A. G.; Boskey, A.; Fleisher, M.
Article Title: Massive solitary tophus containing calcium pyrophosphate dihydrate crystals at the acromioclavicular joint
Abstract: A massive solitary tophus containing calcium pyrophosphate dihydrate (CPPD) crystals was resected from the distal clavicle and proximal acromion of a 62-year-old man who presented with a painful shoulder mass. The diagnosis was confirmed histologically and by X-ray diffraction. CPPD crystal deposition was found within bone, however, the articular cartilage was not involved. Other unusual features of the case include the size of the lesion, the monoarticular presentation and a peculiar discoloration of the overlying skin. The clinical presentation and radiographic features were initially consistent with a malignant process; thus the case demonstrates that CPPD arthropathy should be included in the differential diagnosis of periarticular tumors.
Keywords: adult; aged; bone neoplasms; bone tumor; case report; diagnosis, differential; differential diagnosis; pathology; histology; diagnosis; radiography; bone disease; bone diseases; calcinosis; x ray diffraction; middle age; x-ray diffraction; human; male; article; calcium pyrophosphate; acromioclavicular joint
Journal Title: Clinical Orthopaedics and Related Research
Volume: 227
ISSN: 0009-921X
Publisher: Springer  
Date Published: 1988-02-01
Start Page: 305
End Page: 309
Language: English
DOI: 10.1097/00003086-198802000-00037
PUBMED: 3338220
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
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MSK Authors
  1. Martin Fleisher
    312 Fleisher
  2. John H Healey
    547 Healey
  3. Andrew G Huvos
    289 Huvos
  4. Ralph C. Marcove
    25 Marcove