Blood transfusion and lung cancer recurrence Journal Article


Authors: Keller, S. M.; Groshen, S.; Martini, N.; Kaiser, L. R.
Article Title: Blood transfusion and lung cancer recurrence
Abstract: Recent reports have suggested that perioperative blood transfusions may adversely affect prognosis after resection of non‐small cell lung cancer (NSCLC). To determine the impact of perioperative transfusion on the recurrence‐free interval, the status of 352 patients who underwent pulmonary resection for pathologic Stages I and II NSCLC was investigated. Transfused patients were significantly older than untransfused patients (P = 0.0009) but were not significantly different in sex distribution (P = 0.12) or tumor stage (P = 0.09). Recurrence was not significantly different in transfused patients when compared with patients who received no blood (P = 0.23) even when stratified for stage (Stage I, P = 0.58; Stage II, P = 0.14). Furthermore, the number of units transfused was not associated with time to tumor recurrence (P = 0.58). Contrary to other reports, these results do not support the contention that perioperative blood transfusion is significantly associated with decreased recurrence‐free survival. Copyright © 1988 American Cancer Society
Keywords: aged; major clinical study; cancer recurrence; follow-up studies; neoplasm staging; neoplasm recurrence, local; lung neoplasms; lung cancer; age; intraoperative period; blood transfusion; middle age; complication; prognosis; human; male; female; priority journal; blood groups
Journal Title: Cancer
Volume: 62
Issue: 3
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1988-08-01
Start Page: 606
End Page: 610
Language: English
DOI: 10.1002/1097-0142(19880801)62:3<606::Aid-cncr2820620327>3.0.Co;2-q
PUBMED: 3390797
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
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  1. Nael   Martini
    105 Martini
  2. Susan Groshen
    28 Groshen