Thio-mediated synthesis of derivatized N-linked glycopeptides using isonitrile chemistry Journal Article


Authors: Wu, X.; Yuan, Y.; Li, X.; Danishefsky, S. J.
Article Title: Thio-mediated synthesis of derivatized N-linked glycopeptides using isonitrile chemistry
Abstract: The reaction of oligosaccharide isonitriles with peptide thioacids in the presence of bulky thiophenol as activator to provide N-linked glycopeptides at room temperature is described. © 2009 Elsevier Ltd. All rights reserved.
Keywords: unclassified drug; reaction analysis; chemical reaction; room temperature; glycopeptide; isonitrile derivative; peptide synthesis; thioacid; thiophenol derivative; 2,6 dimethyl thiophenol; oligosaccharide; thiophenol
Journal Title: Tetrahedron Letters
Volume: 50
Issue: 32
ISSN: 0040-4039
Publisher: Pergamon-Elsevier Science Ltd  
Date Published: 2009-08-12
Start Page: 4666
End Page: 4669
Language: English
DOI: 10.1016/j.tetlet.2009.06.005
PROVIDER: scopus
PMCID: PMC2735058
PUBMED: 20161157
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 30 November 2010" - "CODEN: TELEA" - "Source: Scopus"
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  1. Yu-Ren Yuan
    8 Yuan
  2. Xuechen Li
    13 Li
  3. Xiangyang Wu
    12 Wu