The American Brachytherapy Society consensus statement for skin brachytherapy Guidelines


Authors: Shah, C.; Ouhib, Z.; Kamrava, M.; Koyfman, S. A.; Campbell, S. R.; Bhatnagar, A.; Canavan, J.; Husain, Z.; Barker, C. A.; Cohen, G. N.; Strasswimmer, J.; Joshi, N.
Title: The American Brachytherapy Society consensus statement for skin brachytherapy
Abstract: Purpose: Keratinocyte carcinoma (KC, previously nonmelanoma skin cancer) represents the most common cancer worldwide. While surgical treatment is commonly utilized, various radiation therapy techniques are available including external beam and brachytherapy. As such, the American Brachytherapy Society has created an updated consensus statement regarding the use of brachytherapy in the treatment of KCs. Methods: Physicians and physicists with expertise in skin cancer and brachytherapy created a consensus statement for appropriate patient selection, data, dosimetry, and utilization of skin brachytherapy and techniques based on a literature search and clinical experience. Results: Guidelines for patient selection, evaluation, and dose/fractionation schedules to optimize outcomes for patients with KC undergoing brachytherapy are presented. Studies of electronic brachytherapy are emerging, although limited long-term data or comparative data are available. Radionuclide-based brachytherapy represents an appropriate option for patients with small KCs with multiple techniques available. Conclusions: Skin brachytherapy represents a standard of care option for appropriately selected patients with KC. Radionuclide-based brachytherapy represents a well-established technique; however, the current recommendation is that electronic brachytherapy be used for KC on prospective clinical trial or registry because of a paucity of mature data. © 2020 American Brachytherapy Society
Keywords: human tissue; histopathology; patient selection; cancer radiotherapy; basal cell carcinoma; skin cancer; cohort analysis; practice guideline; skin carcinoma; dosimetry; radiation dose fractionation; medical society; brachytherapy; physician; consensus development; radiation therapy; radioisotope; adjuvant radiotherapy; mohs micrographic surgery; cutaneous squamous cell carcinoma; depth of invasion; non melanoma skin cancer; human; priority journal; article; electronic brachytherapy; keratinocyte carcinoma; physicist
Journal Title: Brachytherapy
Volume: 19
Issue: 4
ISSN: 1538-4721
Publisher: Elsevier Science, Inc.  
Date Published: 2020-07-01
Start Page: 415
End Page: 426
Language: English
DOI: 10.1016/j.brachy.2020.04.004
PUBMED: 32409128
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 September 2020 -- Source: Scopus
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  1. Gilad N Cohen
    180 Cohen
  2. Christopher Barker
    218 Barker