Optimizing MR-guided radiotherapy for breast cancer patients Review
| Authors: | Groot Koerkamp, M. L.; Vasmel, J. E.; Russell, N. S.; Shaitelman, S. F.; Anandadas, C. N.; Currey, A.; Vesprini, D.; Keller, B. M.; De-Colle, C.; Han, K.; Braunstein, L. Z.; Mahmood, F.; Lorenzen, E. L.; Philippens, M. E. P.; Verkooijen, H. M.; Lagendijk, J. J. W.; Houweling, A. C.; van den Bongard, H. J. G. D.; Kirby, A. M.; the Breast Tumor Site Group of the International MR Linac Atlantic Consortium |
| Review Title: | Optimizing MR-guided radiotherapy for breast cancer patients |
| Abstract: | Current research in radiotherapy (RT) for breast cancer is evaluating neoadjuvant as opposed to adjuvant partial breast irradiation (PBI) with the aim of reducing the volume of breast tissue irradiated and therefore the risk of late treatment-related toxicity. The development of magnetic resonance (MR)–guided RT, including dedicated MR-guided RT systems [hybrid machines combining an MR scanner with a linear accelerator (MR-linac) or 60Co sources], could potentially reduce the irradiated volume even further by improving tumour visibility before and during each RT treatment. In this position paper, we discuss MR guidance in relation to each step of the breast RT planning and treatment pathway, focusing on the application of MR-guided RT to neoadjuvant PBI. © Copyright © 2020 Groot Koerkamp, Vasmel, Russell, Shaitelman, Anandadas, Currey, Vesprini, Keller, De-Colle, Han, Braunstein, Mahmood, Lorenzen, Philippens, Verkooijen, Lagendijk, Houweling, van den Bongard and Kirby. |
| Keywords: | breast cancer; magnetic resonance imaging (mri); partial breast irradiation; neoadjuvant radiation therapy; mr-guided radiotherapy; mr-linac; hybrid machine |
| Journal Title: | Frontiers in Oncology |
| Volume: | 10 |
| ISSN: | 2234-943X |
| Publisher: | Frontiers Media S.A. |
| Date Published: | 2020-07-28 |
| Start Page: | 1107 |
| Language: | English |
| DOI: | 10.3389/fonc.2020.01107 |
| PROVIDER: | scopus |
| PMCID: | PMC7399349 |
| PUBMED: | 32850318 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 September 2020 -- Source: Scopus |
