Architect i2000 SR has improved turnaround time for infectious disease serology testing over Vitros ECiQ Journal Article


Authors: Cheng, C.; Hauser, J. R.; Otto, C.; Tang, Y. W.
Article Title: Architect i2000 SR has improved turnaround time for infectious disease serology testing over Vitros ECiQ
Abstract: Background: Vitros ECiQ and Architect i2000 SR are two automated instruments used to detect serology biomarkers of hepatitis A, B and C viruses, and HIV infections. We compared performance of the Architect to the Vitro EciQ after implementation at our institution. Methods: A retrospective review was performed to compare patient samples tested on the Vitros ECiQ or Architect for hepatitis and HIV serological assays. The positivity rate, frequency of equivocal results, turnaround times (TAT), and hands-on time (HOT) were analyzed. Results: There was no statistical difference in the positivity rate between the two instruments, with the exception of two assays. An increase in equivocal results was observed for the Architect (0.2% vs 0.5%). Notably, the TAT for the Architect i2000 was shorter for all except one assay (31.6 vs 33.7 hours) and demonstrated improved workflow. Conclusions: Overall, both instruments performed comparably. Architect had shorter TAT over Vitros. © 2020 Elsevier Inc.
Keywords: enzyme immunoassay; anti- hav; anti-hbv; anti-hcv; hiv ag/ab combination; vitros eciq
Journal Title: Diagnostic Microbiology and Infectious Disease
Volume: 97
Issue: 3
ISSN: 0732-8893
Publisher: Elsevier Inc.  
Date Published: 2020-07-01
Start Page: 115049
Language: English
DOI: 10.1016/j.diagmicrobio.2020.115049
PUBMED: 32340767
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 3 August 2020 -- Source: Scopus
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  1. Yi-Wei Tang
    188 Tang
  2. Cindy Lee
    5 Lee
  3. Jocelyn Renee Hauser
    6 Hauser