Whole slide imaging: Technology and applications Review


Authors: Hanna, M. G.; Parwani, A.; Sirintrapun, S. J.
Review Title: Whole slide imaging: Technology and applications
Abstract: Pathology has benefited from advanced innovation with novel technology to implement a digital solution. Whole slide imaging is a disruptive technology where glass slides are scanned to produce digital images. There have been significant advances in whole slide scanning hardware and software that have allowed for ready access of whole slide images. The digital images, or whole slide images, can be viewed comparable to glass slides in a microscope, as digital files. Whole slide imaging has increased in adoption among pathologists, pathology departments, and scientists for clinical, educational, and research initiatives. Worldwide usage of whole slide imaging has grown significantly. Pathology regulatory organizations (ie, College of American Pathologists) have put forth guidelines for clinical validation, and the US Food and Drug Administration have also approved whole slide imaging for primary diagnosis. This article will review the digital pathology ecosystem and discuss clinical and nonclinical applications of its use. © 2020 Lippincott Williams and Wilkins. All rights reserved.
Keywords: protein expression; histopathology; review; validation process; diagnostic accuracy; quality control; image analysis; immunofluorescence; training; algorithm; image quality; artificial intelligence; image processing; kidney biopsy; health care delivery; technology; information technology; personalized medicine; optical coherence tomography; tumor microenvironment; digital pathology; whole slide imaging; computer aided design; applications; machine learning; learning algorithm; image retrieval; human; priority journal
Journal Title: Advances in Anatomic Pathology
Volume: 27
Issue: 4
ISSN: 1072-4109
Publisher: Lippincott Williams & Wilkins  
Date Published: 2020-07-01
Start Page: 251
End Page: 259
Language: English
DOI: 10.1097/PAP.0000000000000273
PUBMED: 32452840
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 3 August 2020 -- Source: Scopus
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  1. Matthew George Hanna
    101 Hanna