Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part II on Urological Management) Review
| Authors: | Rogers, M. J.; Ramirez-Fort, M. K.; Kashanian, J. A.; Broster, S. A.; Matta, J.; Mahase, S. S.; Fort, D. V.; Niaz, M. J.; McClelland, S. 3rd; Bander, N. H.; Fort, M.; Lange, C. S.; Schlegel, P.; Mulhall, J. P. |
| Review Title: | Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part II on Urological Management) |
| Abstract: | Prostate cancer is the most common malignancy in men and the second leading cause of cancer-related death in men. Radiotherapy is a curative option that is administered via external beam radiation, brachytherapy, or in combination. Sexual dysfunction is a common toxicity following radiotherapy, similar to men undergoing radical prostatectomy, but the etiology is different. The pathophysiology of radiation-induced sexual dysfunction is multi-factorial, and the toxicity is a major cause of impaired quality of life among long-term prostate cancer survivors. Management of a patient's sexual function during and after radiotherapy requires multidisciplinary coordination of care between radiation oncology, urology, psychiatry, pharmacy, and dermatology. This review provides a framework for clinicians to better understand prostatic radiotherapy-induced sexual dysfunction diagnosis, evaluation, and a patient-centered approach to toxicity preventive strategies and management. © 2020 |
| Keywords: | review; cancer patient; cancer radiotherapy; quality of life; practice guideline; radiation injury; cancer survivor; prostate cancer; sexual dysfunction; radiation oncology; prostatectomy; long term care; brachytherapy; radiation therapy; physical examination; external beam radiotherapy; erectile dysfunction; phosphodiesterase v inhibitor; surgical patient; intracavernosal injections; penile prosthesis; human; female; vacuum erection device; orgasmic dysfunction; penile vibratory stimulation; ejaculatory dysfunction; pde-5i; sexual toxicities |
| Journal Title: | Reports of Practical Oncology and Radiotherapy |
| Volume: | 25 |
| Issue: | 4 |
| ISSN: | 1507-1367 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2020-07-01 |
| Start Page: | 619 |
| End Page: | 624 |
| Language: | English |
| DOI: | 10.1016/j.rpor.2020.03.011 |
| PROVIDER: | scopus |
| PMCID: | PMC7286930 |
| PUBMED: | 32549795 |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
