Amplification of a polymorphic dihydrofolate-reductase gene expressing an enzyme with decreased binding to methotrexate in a human-colon carcinoma cell-line, HCT-8R4, resistant to this drug Journal Article


Authors: Srimatkandada, S.; Schweitzer, B. I.; Moroson, B. A.; Dube, S.; Bertino, J. R.
Article Title: Amplification of a polymorphic dihydrofolate-reductase gene expressing an enzyme with decreased binding to methotrexate in a human-colon carcinoma cell-line, HCT-8R4, resistant to this drug
Journal Title: Journal of Biological Chemistry
Volume: 264
Issue: 6
ISSN: 0021-9258
Publisher: American Society for Biochemistry and Molecular Biology  
Date Published: 1989-02-25
Start Page: 3524
End Page: 3528
Language: English
ACCESSION: WOS:A1989T275200073
PROVIDER: wos
PUBMED: 2914962
Notes: Article -- Source: Wos
Citation Impact
MSK Authors
  1. Joseph Bertino
    363 Bertino