Unanticipated myocarditis in a surgical patient treated with pembrolizumab: A case report Journal Article
| Authors: | Nierstedt, R. T.; Yeahia, R.; Barnett, K. M. |
| Article Title: | Unanticipated myocarditis in a surgical patient treated with pembrolizumab: A case report |
| Abstract: | We report a case of fatal immune checkpoint inhibitor (ICI)-associated myocarditis in a 77-year-old man with metastatic non-small cell lung cancer (NSCLC) who presented for mediport placement at our outpatient surgical center. He denied any cardiac complaints and had a previously normal electrocardiogram (EKG) off treatment. Intraoperatively and postoperatively, he displayed cardiac rhythm abnormalities. The patient was then transferred to a tertiary facility, where he expired within 48 hours. As cancer immunotherapy becomes increasingly prominent, ICI-associated myocarditis should be considered a potentially critical contributor to perioperative cardiac morbidity and mortality. |
| Keywords: | immunotherapy; receptor; immune |
| Journal Title: | A and A Practice |
| Volume: | 14 |
| Issue: | 6 |
| ISSN: | 2575-3126 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2020-04-01 |
| Start Page: | e01177 |
| Language: | English |
| ACCESSION: | WOS:000531378700006 |
| DOI: | 10.1213/xaa.0000000000001177 |
| PROVIDER: | wos |
| PMCID: | PMC7101019 |
| PUBMED: | 32132361 |
| Notes: | Article -- Source: Wos |
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