Next generation sequencing in gastric or gastroesophageal adenocarcinoma Review


Author: Ku, G. Y.
Review Title: Next generation sequencing in gastric or gastroesophageal adenocarcinoma
Abstract: Seminal analyses of The Cancer Genome Atlas (TGCA) and Asian Cancer Research Group (ACRG) have provided unprecedented insight into the molecular underpinnings of gastric cancer (GC). At the same time, next generation sequencing (NGS) panels, driven by quantum improvements in DNA sequencing technology and bioinformatics, are now routinely used in standard clinical care and also extensively for research purposes. This review article will discuss the molecular subtypes of GC, the current standard-of-care therapies for GC and the role of NGS in standard care and in research. © Translational Gastroenterology and Hepatology. All rights reserved.
Keywords: targeted therapy; next generation sequencing (ngs); gastric cancer (gc)
Journal Title: Translational Gastroenterology and Hepatology
Volume: 5
ISSN: 2415-1289
Publisher: Ame Publ Co  
Date Published: 2020-10-01
Start Page: 56
Language: English
DOI: 10.21037/tgh.2020.01.09
PROVIDER: scopus
PUBMED: 33073051
PMCID: PMC7530318
DOI/URL:
Notes: Review -- Export Date: 1 June 2020 -- Source: Scopus
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  1. Geoffrey Yuyat Ku
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