Why do young people get cancer? Journal Article


Author: Kentsis, A.
Article Title: Why do young people get cancer?
Abstract: Oncologists and cancer biologists are frequently confronted by the question of what causes cancer? This is particularly vexing for cancers affecting children and young adults who have had limited exposure to environmental mutagens and the effects of aging. Here, I focus on a general framework of the causes of early-onset cancer development in children and young adults by relating inherited and constitutional cancer predisposition, oncogenic pathogens, and developmental mutations. This framework has implications not only for mechanistic investigation of young cancers, but should also clarify improved strategies for their treatment, screening, and potential prevention. © 2020 Wiley Periodicals, Inc.
Keywords: tumor biology; oncology; oncogenes; pediatric hematology/oncology
Journal Title: Pediatric Blood and Cancer
Volume: 67
Issue: 7
ISSN: 1545-5009
Publisher: Wiley Periodicals, Inc  
Date Published: 2020-07-01
Start Page: e28335
Language: English
DOI: 10.1002/pbc.28335
PUBMED: 32391946
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 June 2020 -- Source: Scopus
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  1. Alex   Kentsis
    66 Kentsis