MR imaging of the cranial meninges with emphasis on contrast enhancement and meningeal carcinomatosis Journal Article


Authors: Sze, G.; Soletsky, S.; Bronen, R.; Krol, G.
Article Title: MR imaging of the cranial meninges with emphasis on contrast enhancement and meningeal carcinomatosis
Abstract: MR imaging was used to investigate normal and abnormal meningeal enhancement, with an emphasis on meningeal carcinomatosis. Three groups of patients were studied on a 1.5-T system. In group 1, the normal meninges were examined in 20 patients and were found to show fine linear enhancement in short segments, especially in a parasagittal distribution. In group 2, all gadolinium-enhanced head scans were reviewed retrospectively. Abnormal meningeal enhancement was detected in 52 patients. In some of these, the enhancement was associated with pathologic conditions of the meninges, including leptomeningeal tumor and meningeal infections and other inflammatory conditions; in others the enhancement was adjacent to subdural hematomas, subacute infarcts, and skull lesions, such as metastases or postoperative defects. In group 3, 30 cases of meningeal carcinomatosis were studied prospectively. Enhancement was seen in approximately two-thirds of cases and usually was quite diffuse and applied to the inner table of the skull. Frank nodules were seen less often. Contrast-enhanced CT was equal to MR in the detection of nodules but was nearly always unable to show diffuse meningeal enhancement against the inner table of the skull. Contrast-enhanced MR was more sensitive than contrast-enhanced CT in the examination of normal and abnormal meninges. Abnormal findings, such as meningeal carcinomatosis, were demonstrated more often by MR than by CT.
Keywords: adolescent; adult; child; aged; aged, 80 and over; child, preschool; retrospective studies; major clinical study; gadolinium; magnetic resonance imaging; prospective studies; image enhancement; brain; infant; meningeal neoplasms; meninges; carcinoma; brain diseases; contrast media; gadolinium dtpa; nuclear magnetic resonance; organometallic compounds; carcinomatosis; computer analysis; middle age; pentetic acid; meninx; human; male; female
Journal Title: American Journal of Neuroradiology
Volume: 10
Issue: 5
ISSN: 0195-6108
Publisher: American Society of Neuroradiology  
Date Published: 1989-09-01
Start Page: 965
End Page: 975
Language: English
PUBMED: 2505542
PROVIDER: scopus
DOI/URL:
Notes: Article -- Author Richard Bronen's only listed with "present address" on the original publication -- Export Date: 14 April 2020 -- Source: Scopus
Citation Impact
MSK Authors
  1. George Krol
    86 Krol
  2. Gordon Sze
    36 Sze