Carcinoma of major salivary glands: Recent trends Conference Paper


Authors: Spiro, R. H.; Armstrong, J.; Harrison, L.; Geller, N. L.; Lin, S. Y.; Strong, E. W.
Title: Carcinoma of major salivary glands: Recent trends
Conference Title: 2nd International Conference on Head and Neck Cancer
Abstract: We have reviewed a 44-year experience with previously untreated carcinomas arising in major salivary glands to compare 319 patients treated before 1966 with 155 who received therapy between 1966 and 1982. Actuarial analysis indicates that five- and ten-year survival of our more recently treated patients was 80% and 65%, compared with 60% and 50% in patients treated before 1966. Explanation for this includes the higher proportion of patients with less aggressive histologic subtypes seen in recent years, as well as the fact that many of our patients treated before 1966 had surgical procedures considered inadequate by current standards. We also believe that adjunctive radiation oncology enhanced survival, but it could not be proved in this retrospective study. Multivariate analysis confirms that the clinical stage was the most important prognostic variable. (Arch Otolaryngol Head Neck Surg 1989;115:316-321). © 1989, American Medical Association. All rights reserved.
Keywords: adolescent; adult; cancer survival; child; aged; aged, 80 and over; retrospective studies; major clinical study; histopathology; carcinoma, squamous cell; cancer staging; methodology; adenocarcinoma; carcinoma; salivary gland neoplasms; salivary gland carcinoma; carcinoma, adenoid cystic; parotid gland carcinoma; parotid neoplasms; middle age; submandibular gland; abstract report; human; male; female; priority journal; submandibular gland neoplasms; sublingual gland
Journal Title Archives of Otolaryngology - Head & Neck Surgery
Volume: 115
Issue: 3
Conference Dates: 1988 Jul 31-Aug 5
Conference Location: Boston, MA
ISBN: 0886-4470
Publisher: American Medical Association  
Date Published: 1989-03-01
Start Page: 316
End Page: 321
Language: English
DOI: 10.1001/archotol.1989.01860270058015
PUBMED: 2537093
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 14 April 2020 -- Source: Scopus
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MSK Authors
  1. Elliot W Strong
    97 Strong
  2. Ronald H Spiro
    105 Spiro
  3. Louis B Harrison
    123 Harrison
  4. Nancy L. Geller
    65 Geller