Management of cancer pain: Pharmacology and principles of management Journal Article


Author: Inturrisi, C. E.
Article Title: Management of cancer pain: Pharmacology and principles of management
Abstract: The pain of the vast majority of patients with cancer can be controlled with the use of analgesic drugs. Pharmacokinetic and clinical studies have provided the basis for guidelines for the pharmacologic management of cancer pain. The fundamental concept underlying these guidelines is individualization of therapy, which has as its goal the maximization of pain relief and the minimization of adverse drug effects. This article presents these guidelines and discusses the pharmacologic properties and adverse effects of analgesic drugs commonly used in the treatment of cancer pain. Also reviewed are methods for avoiding and treating the adverse effects of analgesics. Copyright © 1989 American Cancer Society
Keywords: unclassified drug; constipation; review; side effect; neoplasms; pain; nausea; vomiting; opiate; sedation; cancer pain; pethidine; acetylsalicylic acid; paracetamol; ibuprofen; naproxen; nonsteroid antiinflammatory agent; methadone; morphine; myoclonus; respiration depression; analgesics, opioid; analgesics; hydromorphone; urine retention; intravenous drug administration; analgesic agent; levorphanol; oxycodone; oral drug administration; intramuscular drug administration; codeine; pentazocine; buprenorphine; dextropropoxyphene; nalbuphine; butorphanol; human; priority journal; support, u.s. gov't, p.h.s.; choline magnesium trisalicylate; diflunisal; fenoprofen; intrathecal drug administration; rectal drug administration; morphine antagonist
Journal Title: Cancer
Volume: 63
Issue: 11
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1989-06-01
Start Page: 2308
End Page: 2320
Language: English
DOI: 10.1002/1097-0142(19890601)63:11<2308::Aid-cncr2820631141>3.0.Co;2-d
PUBMED: 2566371
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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