Prognosis in childhood rhabdomyosarcoma of the extremity Journal Article
| Authors: | Ghavimi, F.; Mandell, L. R.; Heller, G.; Hajdu, S. I.; Exelby, P. |
| Article Title: | Prognosis in childhood rhabdomyosarcoma of the extremity |
| Abstract: | From 1970 to 1987, 34 patients younger than 22 years of age with extremity rhabdomyosarcoma were treated at the Memorial Sloan‐Kettering Cancer Center (MSKCC). All patients were treated according to protocols consisting of surgery, radiotherapy, and multiple drug chemotherapy. Sixteen of 34 patients survived, and 14 continue to be disease‐free; the 5‐year survival rate was 44%. A retrospective univariate analysis of data according to the TNM staging system was undertaken. Tumor invasion, regional nodal in/olvement, distant metastases, and alveolar histologic condition each had a significant impact on survival. However, in multivariate analysis, the stage of disease at diagnosis was the most important predictor of survival outcome. Copyright © 1989 American Cancer Society |
| Keywords: | adolescent; adult; child; clinical article; child, preschool; retrospective studies; combined modality therapy; cancer staging; lymphatic metastasis; neoplasm staging; childhood cancer; limb; infant; amputation; extremities; remission induction; neoplasm invasiveness; rhabdomyosarcoma; fatality; prognosis; human; male; female; priority journal |
| Journal Title: | Cancer |
| Volume: | 64 |
| Issue: | 11 |
| ISSN: | 0008-543X |
| Publisher: | Wiley Blackwell |
| Date Published: | 1989-12-01 |
| Start Page: | 2233 |
| End Page: | 2237 |
| Language: | English |
| DOI: | 10.1002/1097-0142(19891201)64:11<2233::Aid-cncr2820641108>3.0.Co;2-6 |
| PUBMED: | 2804912 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
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