Can local radiofrequency ablation of tumors generate systemic immunity against metastatic disease? Journal Article


Authors: Waitz, R.; Solomon, S. B.
Article Title: Can local radiofrequency ablation of tumors generate systemic immunity against metastatic disease?
Abstract: Radiofrequency (RF) ablation may have the potential to turn a patient's tumor into an endogenous tumor vaccine; in this context of RF ablation-triggered immune system stimulation, the report by Dromi et al (1) demonstrates a systemic immune response after local RF ablation in a mouse model. © RSNA, 2009.
Keywords: signal transduction; controlled study; nonhuman; note; cancer radiotherapy; mouse; animal; animals; mice; animal tissue; cell death; metastasis; cell maturation; cell infiltration; dendritic cell; animal experiment; animal model; tumor regression; pathology; cell line, tumor; tumor antigen; bladder tumor; urinary bladder neoplasms; antigen presentation; immunology; immune response; tumor cell line; neoplasm metastasis; protein secretion; tumor immunity; innate immunity; immunity, innate; immunostimulation; radiofrequency ablation; antigen presenting cell; antigen-presenting cells; t lymphocyte activation; catheter ablation; abscopal effect; experimental model; immunological memory
Journal Title: Radiology
Volume: 251
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 2009-04-01
Start Page: 1
End Page: 2
Language: English
DOI: 10.1148/radiol.2511082215
PUBMED: 19332838
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 30 November 2010" - "CODEN: RADLA" - "Source: Scopus"
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Rebecca Waitz
    13 Waitz
  2. Stephen Solomon
    424 Solomon