The preliminary study on HMBA-induced differentiation of the drug-pretreated murine erythroleukemia cells Journal Article

  


Authors: Chen, Z.; Michaeli, J.; Marks, P. A.; Rifkind, R. A.
Article Title: The preliminary study on HMBA-induced differentiation of the drug-pretreated murine erythroleukemia cells
Abstract: Several drug-resistant variants have been developed by growing the parental MEL cells in presence of colchicine, adriamycin and vincristine respectively with stepwise increasing concentration. Both the colchicine-resistant Sc9(Co10) and vincristine-resistant Sc9(VCR5) cells displayed an accelerated HMBA-induced commitment to terminal cell differentiation, whereas the adriamycin-resistant SC9 (A120) showed no acceleration but rather a substantial delay in HMBA-induced differentiation. The studies provide more clues as well as experimental models for further study on the mechanism of induced differentiation of MEL cells. © 1989 Chinese Journal Of Cancer Research.
Journal Title: Chinese Journal of Cancer Research
Volume: 1
Issue: 3
ISSN: 1000-9604
Publisher: China Anti-Cancer Association  
Date Published: 1989-06-01
Start Page: 24
End Page: 28
Language: English
DOI: 10.1007/bf02684813
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-51649152251&doi=10.1007%2fBF02684813&partnerID=40&md5=23df37398330bcc61518d2a313034203
Notes: Article -- Export Date: 14 April 2020 -- Source: Scopus
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MSK Authors
  1. Joseph Michaeli
    62 Michaeli
  2. Paul Marks
    186 Marks
  3. Richard Rifkind
    118 Rifkind
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