Inability of computed tomography appearance of recurrent malignant astrocytoma to predict survival following reoperation Journal Article


Authors: Wallner, K. E.; Galicich, J. H.; Malkin, M. G.; Arbit, E.; Krol, G.; Rosenblum, M. K.
Article Title: Inability of computed tomography appearance of recurrent malignant astrocytoma to predict survival following reoperation
Abstract: Computed tomogrpahic (CT) scans of 39 patients who underwent reoperation for recurrent malignant astrocytoma at Memorial Sloan-Kettering Cancer Center from1980 through 1987 were reviewed and correlated with the patients' clinical course. Histologic diagnosis (anaplastic astrocytoma v glioblastoma multiforme) had a statistically significant impact on survival following reoperation (P = .038). Patients with high preoperative performance status (P = .29), total resection by postoperative CT scan (P = .15), and frontal lobe tumors (P = .17) tended to survive longer following reoperation. The size of the tumor at the time of recurrence did not correlate with survival following reoperation. Patients with a small amount of peritumoral edema at the time of recurrence tended to survive longer, but the effect was small (P = .16). Prognosis following reoperation cannot be accurately predicted on the basis of tumor appearance on CT scan.
Keywords: clinical article; computer assisted tomography; reoperation; astrocytoma; computer analysis; prognosis; human; priority journal
Journal Title: Journal of Clinical Oncology
Volume: 7
Issue: 10
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 1989-10-01
Start Page: 1492
End Page: 1496
Language: English
DOI: 10.1200/jco.1989.7.10.1492
PUBMED: 2550591
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 14 April 2020 -- Source: Scopus
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MSK Authors
  1. Marc Rosenblum
    424 Rosenblum
  2. Mark Malkin
    38 Malkin
  3. George Krol
    86 Krol
  4. Ehud   Arbit
    66 Arbit
  5. Kent E. Wallner
    48 Wallner