Results of external beam radiation for children with retinoblastoma: A comparison of two techniques Journal Article
| Authors: | McCormick, B.; Ellsworth, R.; Abramson, D.; LoSasso, T.; Grabowski, E. |
| Article Title: | Results of external beam radiation for children with retinoblastoma: A comparison of two techniques |
| Abstract: | From 1979 through 1987, 82 children with retinoblastoma were treated with primary external beam therapy, to one or both eyes. A total of 120 eyes were irradiated, with doses from 3850-5000 cGy. We used a lens-sparing electron beam technique from 1970 to 1984 and a modified lateral beam technique from 1984 to 1987. Comparison of outcome for eyes with Group I-III (Reese-Ellsworth) disease revealed a significant advantage for freedom from relapse favoring the lateral technique (p = 0.0009). A similar trend was noted for final eye outcome (need for enucleation). No differences were noted for eyes with Group IV-V disease. Patient survival was 90% at 4 years, with a mean follow-up time of 36 months. |
| Keywords: | child, preschool; major clinical study; comparative study; methodology; follow-up studies; radiotherapy dosage; radiotherapy; retinoblastoma; infant; eye enucleation; methods; technique; eye neoplasms; prognosis; human; priority journal |
| Journal Title: | Journal of Pediatric Ophthalmology and Strabismus |
| Volume: | 26 |
| Issue: | 5 |
| ISSN: | 0191-3913 |
| Publisher: | SLACK, Inc. |
| Date Published: | 1989-09-01 |
| Start Page: | 239 |
| End Page: | 243 |
| Language: | English |
| PUBMED: | 2795413 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 14 April 2020 -- Source: Scopus |
Citation Impact
Related MSK Work