Painful polyneuropathy Journal Article


Author: Portenoy, R. K.
Article Title: Painful polyneuropathy
Abstract: The development of chronic neuropathic pain associated with peripheral neuropathy poses important diagnostic and therapeutic challenges for the treating practitioner. The clinical assessment must be designed both to identify the underlying etiology of the neuropathy if possible, and to provide a comprehensive understanding of the characteristics and impact of the pain. If primary therapy is available, it should be offered. Concurrently, or in lieu of primary therapy if none is available, a multimodal approach to the pain and related physical, psychological, and social impairments should be undertaken. The treatment approaches are generally extrapolated from anecdotal experience and information gained in other populations. Nonetheless, a systematic and concerted effort to alleviate pain and improve function has the potential to yield results gratifying to both the patient and the clinician.
Keywords: review; neoplasms; pain; opiate; amyloidosis; chronic disease; nonsteroid antiinflammatory agent; diabetes mellitus; hyperthyroidism; clonazepam; fluphenazine; levomepromazine; phenytoin; peripheral nervous system diseases; valproic acid; mexiletine; carbamazepine; insulinoma; alcoholism; clonidine; nutritional deficiency; amitriptyline; metabolic diseases; clomipramine; nortriptyline; antipsychotic agents; antidepressive agents; polyneuropathy; doxepin; imipramine; uremia; baclofen; fabry disease; cancer; human
Journal Title: Neurologic Clinics
Volume: 7
Issue: 2
ISSN: 0733-8619
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 1989-05-01
Start Page: 265
End Page: 288
Language: English
PUBMED: 2566901
PROVIDER: scopus
DOI: 10.1016/s0733-8619(18)30813-2
DOI/URL:
Notes: Review in "Pain: Mechanisms and Syndromes" -- Export Date: 14 April 2020 -- Source: Scopus
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  1. Russell K. Portenoy
    165 Portenoy