Contralateral breast carcinoma: An assessment of risk and prognosis in stage I (T1N0M0) and stage II (T1N1M0) patients with 20-year follow-up Journal Article


Authors: Rosen, P. P.; Groshen, S.; Kinne, D. W.; Hellman, S.
Article Title: Contralateral breast carcinoma: An assessment of risk and prognosis in stage I (T1N0M0) and stage II (T1N1M0) patients with 20-year follow-up
Abstract: Among 644 patients with a small (T1) primary breast carcinoma who were followed up for a median of 18.2 years, subsequent contralateral breast carcinomas were detected in 57 of 610 women (9%) who had a contralateral breast at risk. The average annual hazard rate for contralateral carcinomas was 8 1000 patients at risk per year without significant fluctuations throughout the 20 years of follow-up. Recurrences were caused by 9 of 57 (16%) subsequent contralateral carcinomas, and 4 of the 57 patients (7%) died of recurrent contralateral carcinomas. Contralateral carcinomas were responsible for 5.1% (9 of 176) of all recurrences of breast carcinomas and 2.6% (4 of 153) of breast carcinoma deaths. Surveillance of the contralateral breast must continue throughout a patient's lifetime. Detection and treatment of subsequent lesions at an early stage is a beneficial result of follow-up, especially in women whose first carcinoma is likely to have been cured. © 1989.
Keywords: retrospective studies; major clinical study; comparative study; combined modality therapy; cancer staging; follow up; follow-up studies; neoplasm staging; neoplasm recurrence, local; breast cancer; mastectomy; risk factors; age factors; breast neoplasms; risk factor; time factors; carcinoma in situ; carcinoma; neoplasms, multiple primary; fatality; prognosis; human; female; priority journal
Journal Title: Surgery
Volume: 106
Issue: 5
ISSN: 0039-6060
Publisher: Elsevier Inc.  
Date Published: 1989-11-01
Start Page: 904
End Page: 910
Language: English
PUBMED: 2814824
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 14 April 2020 -- Source: Scopus
Citation Impact
MSK Authors
  1. Paul P Rosen
    201 Rosen
  2. David Kinne
    64 Kinne
  3. Samuel Hellman
    25 Hellman
  4. Susan Groshen
    28 Groshen