How many nodes need to be removed to make esophagectomy an adequate cancer operation, and does the number change when a patient has chemoradiotherapy before surgery? Journal Article
| Authors: | Yeung, J. C.; Bains, M. S.; Barbetta, A.; Nobel, T.; DeMeester, S. R.; Louie, B. E.; Orringer, M. B.; Martin, L. W.; Reddy, R. M.; Schlottmann, F.; Molena, D. |
| Article Title: | How many nodes need to be removed to make esophagectomy an adequate cancer operation, and does the number change when a patient has chemoradiotherapy before surgery? |
| Abstract: | Introduction and Design: Node dissection during esophagectomy is an important aspect of esophageal cancer staging. Controversy remains as to how many nodes need to be resected in order to properly stage a patient and whether the removal of more nodes carries a stage-independent survival benefit. A review of the literature performed by a group of experts in the subject may help define a minimum accepted number of lymph nodes to be resected in both primary surgery and post-induction therapy scenarios. Results and Conclusions: The existing evidence generally supports the goal of obtaining a minimum of 15 lymph nodes for pathological examination in both primary surgery and post-induction therapy scenarios. © 2019, Society of Surgical Oncology. |
| Keywords: | cancer chemotherapy; cancer surgery; cancer radiotherapy; neoadjuvant therapy; cancer staging; antineoplastic agent; lymph node dissection; systematic review; lymph node; esophagus resection; esophagus cancer; pathologist; chemoradiotherapy; human; article |
| Journal Title: | Annals of Surgical Oncology |
| Volume: | 27 |
| Issue: | 4 |
| ISSN: | 1068-9265 |
| Publisher: | Springer |
| Date Published: | 2020-04-01 |
| Start Page: | 1227 |
| End Page: | 1232 |
| Language: | English |
| DOI: | 10.1245/s10434-019-07870-2 |
| PUBMED: | 31605332 |
| PROVIDER: | scopus |
| PMCID: | PMC7561013 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 April 2020 -- Source: Scopus |
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