Obesity, inflammation, and breast cancer Book Section

  


Authors: Iyengar, N. M.; Morris, P. G.; Hudis, C. A.; Dannenberg, A. J.
Editors: Dannenberg, A. J.; Berger, N. A.
Article/Chapter Title: Obesity, inflammation, and breast cancer
Title Series: Energy Balance and Cancer
Abstract: Obesity, which is rising in incidence worldwide, is important with regard to the treatment of breast cancer, disease progression, and carcinogenesis. Obesity is a risk factor for the development of hormone receptor-positive breast cancer in postmenopausal women and is associated with reduced benefits from treatment. Furthermore, irrespective of breast cancer subtype, obesity is associated with worse outcomes after diagnosis. There is increasing evidence of specific biological underpinnings for these observations, including higher circulating estrogen levels, insulin resistance, altered levels of adipokines, and the consequences of chronic in-breast inflammation. Increasing adiposity also has important implications for local therapy including surgery and radiotherapy. This chapter reviews the complex interactions between obesity and breast cancer. © Springer Science+Business Media New York 2013.
Book Title: Obesity, Inflammation and Cancer
ISBN: 9781461468196
Publisher: Springer New York  
Publication Place: New York, NY
Date Published: 2013-01-01
Start Page: 181
End Page: 217
Language: English
DOI: 10.1007/978-1-4614-6819-6_8
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84985001114&doi=10.1007%2f978-1-4614-6819-6_8&partnerID=40&md5=8e062917cc3ca1bffebeeed5bd1db23a
Notes: Book Chapter: 8 -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Patrick Glyn Morris
    116 Morris
  2. Clifford Hudis
    905 Hudis
  3. Neil Mukund Iyengar
    150 Iyengar
Related MSK Work